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Sensorineural hearing loss and the incidence of Cx26 mutations in Austria

✍ Scribed by Löffler, Judith; Nekahm, Doris; Hirst-Stadlmann, Almut; Günther, Barbara; Menzel, Hans-Jürgen; Utermann, Gerd; Janecke, Andreas R


Book ID
110025098
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
108 KB
Volume
9
Category
Article
ISSN
1018-4813

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Hereditary hearing loss (HHL) is an extremely common disorder. About 70% of HHL is non-syndromic, with autosomal recessive forms accounting for ~ 85% of the genetic load. Although very heterogeneous, the most common cause of HHL in many different world populations is mutations of GJB2, a gene that e