Sensitization to hyperthermia induced in a normal tissue by step-down heating

Sensitization to cisplatin action by ste

Sensitization to cisplatin action by step-down heating in cddp-sensitive and -resistant cells

✍ Judith V. E. Hettinga; Willy Lemstra; Elisabeth G. E. De Vries; Antonius W. T. K 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 494 KB

Hyperthermia treatment (243°C) has been shown to be able to (partially) reverse acquired cDDP resistance. However, such heat treatment is difficult to achieve in the clinic. Short pre-treatment at a high temperature (>42"C), immediately before a treatment at a lower temperature (<42"C) can enhance t