Logarithmic sensitivity coefficients were promulgated for the analysis of metabolic regulation about 20 years ago. Interest in their use has risen significantly since their introduction. However, no comprehensive evaluation of the utility of these metabolic sensitivity coefficients is available for
Sensitivity to values of the rate constants in a neurochemical metabolic model
โ Scribed by Michael C. Kohn; Ernest Chiang
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 721 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0022-5193
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
It is well known that the rate of convergence of the extremes in an iid sample of univariate random variables is determined by the distance of the underlying distribution from a generalized Pareto distribution. We extend this result to higher dimensions.
The objective of this work was to develop a simple residual method to estimate the rate constant for actual or apparent zero-order absorption into a one-compartment model. The method is based on the fact that, in theory, a plot of residuals versus e 7Kt is linear for a zero-order absorption process,
The integration of large quantities of biological information into mathematical models of cell metabolism provides a way for quantitatively evaluating the effect of parameter changes on simultaneous, coupled, and, often, counteracting processes. From a practical point of view, the validity of the mo