To investigate the roles played by the multidrug resistance-associated protein (MRP1) homologues MRP3 and MRP4 in resistance to platinum drugs, we examined steady-state levels of mRNA for both MRP3 and MRP4 in normal lung and lung cancer specimens as well as peripheral mononuclear cells (PMN) after
Sensitivity of the association between increased lung cancer risk and bitumen fume exposure to the assumptions in the assessment of exposure
โ Scribed by Frank de Vocht; Igor Burstyn; Gilles Ferro; Ann Olsson; Mia Hashibe; Hans Kromhout; Paolo Boffetta
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 324 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0340-0131
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To investigate the role of the multidrug resistance-associated protein (MRP1) homologue MRP5 in relation to platinum drug resistance, we examined the steady-state levels of the mRNAs for MRP5 in both lung cancer cell lines and peripheral mononuclear cells (PMN) after exposure to platinum drug and in
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## Abstract ## Background The ageโadjusted incidence rate of breast cancer has increased for Israeli women. Our aim was to explore the hypothesis that occupational exposures are important risk factors, taking into consideration main known risk factors. ## Methods The study population included 32