## Abstract Standardized procedures were developed to compare quantitatively the toxic and transforming effects of ten environmentβrelated polycyclic aromatic hydrocarbons (PAH's) using early passage mixed cultures of fetal Syrian golden hamster lung cells. Evaluation of toxicity was attempted by a
β¦ LIBER β¦
Sensitivity of Syrian golden hamster fetal lung cells to benzo[a]pyrene and other polycyclic hydrocarbons in vitro
β Scribed by Makito Emura; Hans-Bernhard Richter-Reichhelm; Peter Schneider; Ulrich Mohr
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 247 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0300-483X
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## BACKGROUND. Because only a fraction of smokers develop neoplastic lesions, host factors may affect their susceptibility to the carcinogenic effects of tobacco smoke. Benzo[a]pyrene diol epoxide (BPDE) is the metabolic product of benzo[a]pyrene (B[a]P), a constituent of tobacco smoke. Therefore,