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SENSITIVITY OF HUMAN FETAL HEMOPOIETIC CELLS TO NK CELL-MEDIATED LYSIS

✍ Scribed by Lassila, OLLI


Book ID
114822166
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
400 KB
Volume
94C
Category
Article
ISSN
0108-0202

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We have examined the effect of various cell monolayers on the ability of mouse spleen cells to lyse tumor cell targets (natural cytotoxicity reaction). Natural killer (NK) cell activity was reduced by as much as 75% depending on the cell substrate, with the greatest protection afforded by endothelia