Sensitivity and resistance of human tumour cells to interferon rIn ·rCn
✍ Scribed by Lin, Stanley L.; Greene, James J.; Ts'o, P. O. P.; Carter, W. A.
- Book ID
- 109726579
- Publisher
- Nature Publishing Group
- Year
- 1982
- Tongue
- English
- Weight
- 391 KB
- Volume
- 297
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/297417a0
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Metastatic testicular germ cell tumours can be cured using cisplatin-based combination chemotherapy. To investigate the role of DNA repair in cisplatin sensitivity, we measured the formation and removal of cisplatin adducts in the whole genome and in specific genomic regions in 3 testis and 3 bladde
Testicular germ cell tumoun (TGCT) are cured in over 80% of patients by using combination chemotherapy. However, the mechanism regulating this sensitivity has not been defined. Because cells derived from patients with DNA repair syndromes are similar to TCGT in their sensitivity to certain DNA-damag