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Sensitive liquid chromatographic method for the determination of hydrochlorothiazide in human plasma

โœ Scribed by Connie T. Azumaya


Book ID
108449641
Publisher
Elsevier Science
Year
1990
Weight
383 KB
Volume
532
Category
Article
ISSN
0378-4347

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A simple, rapid, sensitive and specific liquid chromatography-tandem mass spectrometry method was developed and validated for quantification of hydrochlorothiazide (I), a common diuretic and anti-hypertensive agent. The analyte and internal standard, tamsulosin (II) were extracted by liquid-liquid e