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Sensitive HPLC–PDA determination of tamoxifen and its metabolites N-desmethyltamoxifen, 4-hydroxytamoxifen and endoxifen in human plasma

✍ Scribed by Antunes, Marina Venzon; Rosa, Daniela Dornelles; Viana, Tamyris dos Santos; Andreolla, Huander; Fontanive, Tiago Ozelame; Linden, Rafael


Book ID
123266593
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
482 KB
Volume
76
Category
Article
ISSN
0731-7085

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A high-performance liquid chromatographic method using a fluorometric detector was developed for the determination of plasma concentrations of the antidepressant indalpine (I) and its major metabolite 4-[2-(3-indolyl)ethyl]-2-piperidinone (PK). the same procedure was used to measure, in urine, level