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Sensitive determination of methotrexate in monkey plasma by high-performance liquid chromatography using on-line solid-phase extraction

✍ Scribed by Teruaki Okuda; Michio Motohashi; Isamu Aoki; Takatsuka Yashiki

Publisher
Elsevier Science
Year
1994
Weight
475 KB
Volume
662
Category
Article
ISSN
0378-4347

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Rapid determination of methotrexate in p
Rapid determination of methotrexate in plasma by high-performance liquid chromatography with on-line solid-phase extraction and automated precolumn derivatization
✍ Samy Emara; Hassan Askal; Tsutomu Masujima πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 66 KB πŸ‘ 2 views

A high-performance liquid chromatographic system, combining solid-phase extraction and automated precolumn derivatization is described for the routine determination of methotrexate in human plasma. The sample extraction and elution onto the analytical column were performed automatically and concomit