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Sensitive detection of tumour cells in effusions by combining cytology and fluorescence in situ hybridisation (FISH)

✍ Scribed by Fiegl, M; Massoner, A; Haun, M; Sturm, W; Kaufmann, H; Hack, R; Krugmann, J; Fritzer-Szekeres, M; Grünewald, K; Gastl, G


Book ID
109998133
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
126 KB
Volume
91
Category
Article
ISSN
0007-0920

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Interphase cytogenetics by fluorescence in situ hybridization (FISH) can be used to detect malignant cells characterized by chromosomal aneuploidy. However, apparent aneusomy in normal ''control'' tissues has to be considered when using FISH as diagnostic tool. In effusions as model tissue exposed t