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Sensitive and quantitative detection of botulinum neurotoxin in neurons derived from mouse embryonic stem cells

โœ Scribed by Sabine Pellett; Zhong-wei Du; Christina L. Pier; William H. Tepp; Su-chun Zhang; Eric A. Johnson


Book ID
116301159
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
492 KB
Volume
404
Category
Article
ISSN
0006-291X

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## Abstract A reliable method to induce neural progenitor/stem cells (NPCs) into dopaminergic (DAergic) neurons has not yet been established. As well, the mechanism involved remains to be elucidated. To induce DAergic differentiation from NPCs, a cytokine mixture (Cโ€Mix) of interleukin (IL)โ€1ฮฒ, ILโ€