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Semisynthetic Approach for Site-Specific Mutations in the α-Chain of Hemoglobin S

✍ Scribed by GIRISH SAHNI; A. SEETHARAMA ACHARYA


Book ID
119863417
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
96 KB
Volume
565
Category
Article
ISSN
0890-6564

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Multiple structural genes for the α chai
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There are two forms of the alpha chain of canine hemoglobin differing only at residue 130. One form (taualpha) contains threonine at this position, the other (Aalpha) contains alanine. Studies of two Labrador dog families strongly support the existance of multiple alpha-chain structural genes as the