PEL: an unbiased method for estimating a
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F. Alarcon; C. Bourgain; M. Gauthier-Villars; V. Planté-Bordeneuve; D. Stoppa-Ly
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Article
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2009
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John Wiley and Sons
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English
⚖ 146 KB
## Abstract Providing valid risk estimates of a genetic disease with variable age of onset is a major challenge for prevention strategies. When data are obtained from pedigrees ascertained through affected individuals, an adjustment for ascertainment bias is necessary. This article focuses on ascer