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Semiempirical MO study of pyruvate substrate behavior in the active center of lactate dehydrogenase

✍ Scribed by Jiří Krechl; Josef Kuthan

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
409 KB
Volume
24
Category
Article
ISSN
0020-7608

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📜 SIMILAR VOLUMES

Molecular orbital study on the active ce
Molecular orbital study on the active center of lactate dehydrogenase
✍ Jiří Krechl; Josef Kuthan 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 470 KB

## Abstract In the active site of lactate dehydrogenase important roles are given to aminoacids His195 and Arg171. The coenzyme nicotinamide adenine dinucleotide (NAD) is required in oxidized form (NAD^+^) for the enzymatic oxidation of the substrate __L__‐lactate. Molecular orbital methods CNDO/2,

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