Semicontinuous granulation—the process of choice for the production of pharmaceutical granules?
✍ Scribed by Juergen Werani; Mads Grünberg; Christian Ober; Hans Leuenberger
- Book ID
- 113860850
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 201 KB
- Volume
- 140
- Category
- Article
- ISSN
- 0032-5910
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📜 SIMILAR VOLUMES
Co-melt granulation of lactose and PEG was investigated in a fluidised bed granulator. The effect of process parameters such as binder content and binder viscosity were correlated to granulation time and particle size distribution. The experimental data indicated that after initial nucleation the gr
mined from results with ejected tablets indicate that higher pressures are needed to fill the interparticulate void space than are in fact necessary. The effect of particle size is less clearly defined in the values of kl and kz but, again, there is the indication that the 75-104-pm. size fraction i