Semi-automated diagnosis of cervical intra-epithelial neoplasia grade 2 by the measurement of acid labile DNA in cytologically normal nucle

A semi-automated procedure for aiding th

A semi-automated procedure for aiding the diagnosis of cervical neoplasms based on the measurement of acid-labile dna in exfoliated cells

✍ A. M. Sincock; J. Middleton 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 French ⚖ 362 KB

## Abstract Measurements of acid‐labile fractions of DNA in cells exfoliated from cervical neoplasms (invasive squamous‐cell carcinomas) using Feulgen techniques have shown elevated values in both abnormal and cytologically normal cell nuclei. These increased values occur early in the hydrolysis pr