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Self-Promoted Nucleophilic Addition of Hexafluoro-2-propanol to Vinyl Ethers.

โœ Scribed by Andrea Di Salvo; Marc David; Benoit Crousse; Daniele Bonnet-Delpon


Publisher
John Wiley and Sons
Year
2006
Weight
21 KB
Volume
37
Category
Article
ISSN
0931-7597

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Self-Promoted Nucleophilic Addition of H
โœ Andrea Diโ€…Salvo; Marc David; Benoรฎt Crousse; Daniรจle Bonnet-Delpon ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 128 KB ๐Ÿ‘ 2 views

## Abstract In spite of its low nucleophilicity, hexafluoroโ€2โ€propanol easily adds to vinyl ethers, without catalyst, to afford a range of hexafluoroisopropyloxy acetals. This addition reaction also occurred in the presence of a competitive, more nucleophilic alcohol. Kinetic studies showed the imp