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Self-inactivating helper virus for the production of high-capacity adenoviral vectors

✍ Scribed by Gonzalez-Aparicio, M; Mauleon, I; Alzuguren, P; Bunuales, M; Gonzalez-Aseguinolaza, G; San Martín, C; Prieto, J; Hernandez-Alcoceba, R

Book ID
109855552
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
545 KB
Volume
18
Category
Article
ISSN
0969-7128

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## Abstract ## Background The ability to induce cytotoxic T lymphocyte (CTL) responses that are multispecific is considered to comprise an essential feature for an efficacious genetic vaccine against many pathogens including HIV and hepatitis C virus. ΔE1Ad vectors are promising vectored vaccines