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Self-Associated Submicron IgG1 Particles for Pulmonary Delivery: Effects of Non-ionic Surfactants on Size, Shape, Stability, and Aerosol Performance

โœ Scribed by Asha R. Srinivasan, Sunday A. Shoyele


Book ID
120958414
Publisher
Springer US
Year
2012
Tongue
English
Weight
525 KB
Volume
14
Category
Article
ISSN
1530-9932

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Self-Associated Submicron IgG1 Particles
โœ Asha R. Srinivasan, Sunday A. Shoyele ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› Springer US ๐ŸŒ English โš– 525 KB

The ability to produce submicron particles of monoclonal antibodies of different sizes and shapes would enhance their application to pulmonary delivery. Although non-ionic surfactants are widely used as stabilizers in protein formulations, we hypothesized that non-ionic surfactants will affect the s