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Self-assembled thermo- and pH responsive micelles of poly(10-undecenoic acid-b-N-isopropylacrylamide) for drug delivery

โœ Scribed by Hua Wei; Xian-Zheng Zhang; Han Cheng; Wen-Qin Chen; Si-Xue Cheng; Ren-Xi Zhuo


Book ID
113691333
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
509 KB
Volume
116
Category
Article
ISSN
0168-3659

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An amphiphilic diblock copolymer of poly(acrylic acid-b-DL-lactide) (PAAc-b-PDLLA) was synthesized by ring-opening polymerization of DL-lactide initiated by hydroxyl-terminated polyacrylic acid (PAAc-OH). The critical micelle concentration (CMC) of PAAc-b-PDLLA in aqueous solution, determined by flu