This book will describe fundamentals and recentย developments in the area ofย Self-Assembled Supramolecular Architecture and their relevance to theย understanding of the functionality ofย membranesย as delivery systems for active ingredients. As the heirarchial architectures determine their performance capabilities, attention will be paid to theoretical and design aspects related to the construction of lyotropic liquid crystals: mesophases such as lamellar, hexagonal, cubic, sponge phase micellosomes. The book will bring to the reader mechanistic aspects, compositional considerations, transition within phases, solubilization capacities, drug entrapment and release mechanisms and transmembrane, transdermal, and other transport phenomena.ย It will stress the importance of these mesostructures to crystallization and polymorphism of drugs, fats, and nutraceuticals and will discuss regioselectivity of organic and enzymatic reactions that take placeย atย interfaces and within the channels of the mesophase. The book will bring studies on the use of these mesophase as crystallization or particulation media for the formation of nanoparticles and nanocrystals.ย Chapters will discuss applications in the areas of pharmaceuticals, food, cosmetics, plastics, paper, agro-chemistry and industrial applications.Content:
Chapter 1 Physics of Self?Assembly of Lyotropic Liquid Crystals (pages 1โ20): Raffaele Mezzenga
Chapter 2 Rheological Theory and Simulation of Surfactant Nematic Liquid Crystals (pages 21โ77): Alejandro D. Rey and E. E. Herrera?Valencia
Chapter 3 Dividing Planes of Hexagonal HII Mesophase (pages 79โ96): Vesselin Kolev, Abraham Aserin and Nissim Garti
Chapter 4 Nanocharacterization of Lyotropic Liquid Crystalline Systems (pages 97โ127): Patrick G. Hartley and Hsin?Hui Shen
Chapter 5 Self?Assembly in Lipidic Particles (pages 129โ155): Anan Yaghmur and Otto Glatter
Chapter 6 Hierarchically Organized Systems Based on Liquid Crystalline Phases (pages 157โ191): Chandrashekhar V. Kulkarni and Otto Glatter
Chapter 7 Synthesis and Alignment of Nanostructured Materials Using Liquid Crystals (pages 193โ218): Idit Amar?Yuli, Abraham Aserin and Nissim Garti
Chapter 8 Recent Developments in Lyotropic Liquid Crystals as Drug Delivery Vehicles (pages 219โ256): Dima Libster, Abraham Aserin and Nissim Garti
Chapter 9 Stimuli?Responsive Lipid?Based Self?Assembled Systems (pages 257โ288): Ben J. Boyd and Wye?Khay Fong
Chapter 10 Nonlamellar Lipid Liquid Crystalline Structures at Interfaces (pages 289โ318): Debby P. Chang and Tommy Nylander
Chapter 11 Multicompartment Lipid Nanocarriers for Targeting of Cells Expressing Brain Receptors (pages 319โ355): Claire Geral, Angelina Angelova, Borislav Angelov, Valerie Nicolas and Sylviane Lesieur