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Self-assembled nanoparticle drug delivery systems from galactosylated polysaccharide–doxorubicin conjugate loaded doxorubicin

✍ Scribed by Yu Cao; Ying Gu; Hong Ma; Jing Bai; Lina Liu; Peiguang Zhao; Hongxuan He


Book ID
116542221
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
400 KB
Volume
46
Category
Article
ISSN
0141-8130

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A pH-sensitive nano drug delivery system
✍ Dianxiang Lu; Xiantao Wen; Jie Liang; Zhongwei Gu; Xingdong Zhang; Yujiang Fan 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 273 KB

## Abstract A novel pH‐sensitive nanoparticle drug delivery system for doxorubicin (DOX) is prepared. Pullulan, a natural biocompatible polysaccharide, was partly carboxymethylized; hydrazine hydrate was condensed with the carboxyl groups forming hydrazide. The hydrazide was coupled with DOX throug