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Self-Aggregated Dinuclear Lanthanide(III) Complexes as Potential Bimodal Probes for Magnetic Resonance and Optical Imaging

✍ Scribed by Regueiro-Figueroa, Martín; Nonat, Aline; Rolla, Gabriele A.; Esteban-Gómez, David; de Blas, Andrés; Rodríguez-Blas, Teresa; Charbonnière, Loïc J.; Botta, Mauro; Platas-Iglesias, Carlos


Book ID
120986893
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
681 KB
Volume
19
Category
Article
ISSN
0947-6539

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Enzyme-responsive MRIcontrast agents containing a "self-immolative" benzylcarbamate moiety that links the MRI-reporter lanthanide complex to a specific enzyme substrate have been developed. The enzymatic cleavage initiates an electronic cascade reaction that leads to a structural change in the Ln II