Selenophosphonates as building blocks for the preparation of bis-methylene analogs of triphosphates

✍ Scribed by Stéphane Mons; Emmanuel Klein; Charles Mioskowski; Luc Lebeau

• Book ID: 104231149
• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 67 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)01088-7

✦ Synopsis

A new route to bis-methylene analogs of triphosphate esters involving carbanion chemistry is described. Lithiated methaneselenophosphonate anion is condensed several times with chlorophosphites and phosphoramidous chlorides prior to esterification/transesterification and selenation or oxidation.