Selenium treatment in neuronal ceroid-lipofuscinosis
โ Scribed by Naidu, Sakkubai ;Maumanee, Irene ;Olson, Jean ;Borel, Janet ;Moser, Hugo ;Opitz, John M. ;Reynolds, James F. ;Pullarkat, Raju K.
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 442 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0148-7299
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We have found a group of individuals with the late infantile, the early juvenile variant, and juvenile neuronal ceroid-lipofuscinosis (NCL) in Newfoundland, an island with a population of 500,000. In the past 25 yr, we have ascertained 44 cases of NCL in 32 sibships: 32 cases of late infantile NCL (
The neuronal ceroid lipofuscinoses are among the most common forms of progressive neurodegenerative disease of childhood. They appear to be panethnic, but there is a special predilection of the infantile subtype in Finland. In the United States, the Batten disease registry of 731 cases shows that ju
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