Enhanced protection to Mycobacterium tub
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Paul S. Redford; Andre Boonstra; Simon Read; Jonathan Pitt; Christine Graham; Ev
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Article
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2010
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John Wiley and Sons
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English
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IL-10 regulates the balance of an immune response between pathogen clearance and immunopathology. We show here that __Mycobacterium tuberculosis__ (__Mtb__) infection in the absence of IL-10 (IL-10^โ/โ^ mice) results in reduced bacterial loads in the lung. This reduction was preceded by an accelerat