Selenium in human plasma: Levels in blood proteins and behavior upon dialysis, acidification, and reduction
✍ Scribed by W.J. Rhead; G.A. Evans; G.N. Schrauzer
- Publisher
- Elsevier Science
- Year
- 1974
- Weight
- 449 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0006-3061
No coin nor oath required. For personal study only.
✦ Synopsis
A number of human blood proteins and other proteins were analyzed for selenium. as was whole human plasma after dialysis under various conditions; the proportions of acid-volatile and zinc-HCl reducible selenium in plasma were aLso determined. Excluding ceruloplasmin and the QI globulins, which have elevated selenium contents, the selenium levels of most proteins ap+ar to parallel their sulfur contents. Only 30% of native plasma selenium can be mobilized by diiysis against reducing or chelating agents or reduced to H&e by vigorous reduction with Zn-HCl; our results are compared to those of other studies employing %eC~'. Contrary to earlier reports, selenate is reduced to H&z by 2%HCl, indicating that this method of reduction is not specific for selenite.