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Selektive Synthesen mit Organometallen III. (Z)-Crotylalkoholate mit metalltragenden olefinischen Kohlenstoffatomen

✍ Scribed by Manfred Schlosser; Erwin Hammer


Publisher
John Wiley and Sons
Year
1974
Tongue
German
Weight
258 KB
Volume
57
Category
Article
ISSN
0018-019X

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✦ Synopsis


1‐Lithiumoxy‐2‐buten‐2‐yl‐lithium and 1‐lithiumoxy‐2‐buten‐3‐yl‐lithium, both as pure (Z)‐stereoisomers, are easily obtained by halogen/metal exchange between s‐butyllithium and (E)‐2‐bromo or (E)‐3‐bromo 2‐buten‐1‐ol, respectively. The starting materials are readily available through dehydrobromination of threo‐2, 3‐dibromo 1‐butanol. The new organolithium compounds are useful intermediates for the preparation of configurationally homogeneous, specifically substituted and branched alkenols.