TOXICOKINETIC EVALUATION OF A SELEGILINE
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JEFFREY S. BARRETT; ANTHONY R. DISANTO; PETER J. THOMFORD; ERIC M. LARSEN; MATTH
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Article
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1997
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John Wiley and Sons
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English
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The toxicology and toxicokinetics of a selegiline transdermal system (STS) were evaluated in a 3 month dog study of daily 24 h applications of placebo 4, 8, or 12 STSs in 32 male and 32 female beagle dogs. Each STS delivered approximately 5 mg selegiline over 24 h. No drug-related signs of toxicity