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Selegiline transdermal system: Current awareness and promise

โœ Scribed by Chi-Un Pae; Hyun-Kook Lim; Changsu Han; Ajwani Neena; Chul Lee; Ashwin A. Patkar


Book ID
116841038
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
299 KB
Volume
31
Category
Article
ISSN
0278-5846

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TOXICOKINETIC EVALUATION OF A SELEGILINE
โœ JEFFREY S. BARRETT; ANTHONY R. DISANTO; PETER J. THOMFORD; ERIC M. LARSEN; MATTH ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 727 KB

The toxicology and toxicokinetics of a selegiline transdermal system (STS) were evaluated in a 3 month dog study of daily 24 h applications of placebo 4, 8, or 12 STSs in 32 male and 32 female beagle dogs. Each STS delivered approximately 5 mg selegiline over 24 h. No drug-related signs of toxicity