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Selegiline as primary treatment in early phase Parkinson's disease — an interim report

✍ Scribed by V. V. Myllylä; K. A. Sotaniemi; J. Tuominen; E. H. Heinonen


Book ID
114782840
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
332 KB
Volume
80
Category
Article
ISSN
0001-6314

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Selegiline (10 mg per day) selectively inhibits monoamine oxidase type B and thus thwarts the metabolism of dopamine by this enzyme. Selegiline has been used in the therapy of Parkinson's disease since 1986. It enhances the efficacy of levodopa, allows a reduction of the levodopa dose, and improves