Selective muscarinic agonists might be useful in the treatment of Alzheimer's disease. Previous studies identified several amidine derivatives as selective and efficacious m1 agonists, using muscarinic receptor subtypes expressed in cell lines. In the present studies, the functional selectivities, s
โฆ LIBER โฆ
Selectivity of oxomemazine for the M1muscarinic receptors
โ Scribed by Shin Woong Lee; Chang Woo Woo; Jeung Gu Kim
- Book ID
- 112961745
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 862 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0253-6269
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Anticholinergic drugs are used to treat a number of neurologic disorders, inctuding parkinsonism, vestibular disturbances, and dystonia. Traditionally, these drugs have been thought to act in similar fashion, as competitive antagonists at a single class of muscarink receptors, and not to differ sign