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Selectivity of Molecular Recognition Displayed by Monoclonal Antibodies as Compared to Receptors – a New Approach to Screen Combinatorial Libraries

✍ Scribed by Oliver Lack; Walter Huber; Wolf-D. Woggon


Publisher
John Wiley and Sons
Year
2003
Tongue
German
Weight
167 KB
Volume
86
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Photolabeled monoclonal antibodies generated against a potent antagonist of the glycoprotein receptor GPIIb‐IIIa have been used to demonstrate that antibodies can be employed to replace receptors for on‐bead screening of combinatorial libraries.