Selectivity of bifunctional annulating reagents: Additional rules for ring closure

✍ Scribed by Thomas V. Lee; Frances S. Roden; Helena T-L. Yeoh

• Book ID: 104222184
• Publisher: Elsevier Science
• Year: 1990
• Tongue: French
• Weight: 227 KB
• Volume: 31
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)88916-9

✦ Synopsis

Suwnary:-From a consideration of the products of cyclisation of [email protected]!anes it is concluded that stereoelectronic #ects pkay a dominant r&e and that descriptors, similar to those for predicting intramolecular aldol cyclisations, could be usedfor intramolecular cyclisations of allylic species.

Multi-functional compounds are becoming increasingly important in organic synthesis, not least because of the potential they offer for performing highly efficient multi-bond forming reactions. For