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Selectivity in solute transport: Binding sites and channel structure in maltoporin and other bacterial sugar transport proteins

✍ Scribed by Thomas Ferenci


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
668 KB
Volume
10
Category
Article
ISSN
0265-9247

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✦ Synopsis


A stereospeclfc binding site is not the only determinant governing the selectivity of transport proteins. An understanding of transport across cellular membranes requires a description of the diferent compartments within a transmembrane channel; evidence for the existence of these compartments comes from the selectivity properties of genetically modified maltoporin. Such compartments may also be of signlfcance in determining the speciJicity of other transport proteins.