Selectivity in palladium catalyzed arylation: Synthetic application leading to aromatized ionone natural products

✍ Scribed by Hisahiro Hagiwara; Yasushi Eda; Kimie Morohashi; Toshio Suzuki; Masayoshi Ando; Nobuhiko Ito

• Book ID: 104259258
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 200 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)00657-1

✦ Synopsis

The selectivity in aromatic substitution vs conjugate addition during palladium catalyzed reactions has been controlled simply by changing the base. These reaction conditions have been applied to the syntheses of aromatized 13-ionone natural products 1 and its dihydroderivatives 7.