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Selectively desulfated heparin inhibits P-selectin-mediated adhesion of human melanoma cells

✍ Scribed by Min Wei; Yanguang Gao; Meihong Tian; Na Li; Shui Hao; Xianlu Zeng

Book ID: 116333603
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 83 KB
Volume: 229
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2005.01.034

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## Abstract The adhesion of tumor cells with platelets is important in the process of tumor metastasis. A huge work has indicated that anti‐adhesion is an effective strategy for metastasis inhibition. In this article, we assess the role of platelet integrin α~IIb~β~3~ in adhesion of melanoma cells