Selective versus exclusive use of sirolimus-eluting stent implantation in multivessel coronary artery disease

✍ Scribed by William W. Chu; Seung-Woon Rha; Pramod K. Kuchulakanti; Edouard Cheneau; Rebecca Torguson; Rajbabu Pakala; Ellen E. Pinnow; Augusto D. Pichard; Lowell F. Satler; Kenneth M. Kent; Joseph Lindsay; Ron Waksman

• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 52 KB
• Volume: 65
• Category: Article
• ISSN: 1522-1946
• DOI: 10.1002/ccd.20431

✦ Synopsis

Sirolimus-eluting stents (SESs; Cypher) have demonstrated a significant reduction in restenosis rates when compared to bare metal stents (BMSs). The purpose of this study was to evaluate the strategy of exclusive use of two SESs versus the combination of one BMS and one SES for two-vessel coronary artery disease (CAD). It was found that the selective use of one SES combined with one BMS in patients undergoing percutaneous coronary intervention that requires more than one stent is safe, feasible, and associated with favorable procedural, 30-day, and 6-month clinical outcomes when compared to the exclusive use of SESs.