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Selective thromboxane synthetase inhibitors. 3. 1H-Imidazol-1-yl-substituted benzo[b]furan-, benzo[b]thiophene- and indole-2- and 3-carboxylic acids

✍ Scribed by Cross, Peter E.; Dickinson, Roger P.; Parry, M. John; Randall, Michael J.


Book ID
119939282
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
876 KB
Volume
29
Category
Article
ISSN
0022-2623

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## Abstract magnified image Reactions of 3‐chlorobenzo[__b__]thiophene‐2‐carbonyl chloride with 2‐alkyl‐2‐aminopropanamides have been used to prepare a series of carboxamides **1a‐d** (yields 61‐85%). The products were submitted to base‐catalysed ring closure reactions to give the corresponding 4,