Selective synthesis of 1,1′-binaphthalene derivatives by oxidative coupling with TiCl4

✍ Scribed by Joël Doussot; Alain Guy; Clotilde Ferroud

• Book ID: 104210079
• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 89 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)00206-9

✦ Synopsis

Oxidative coupling of naphthalene compounds with TiCl 4 in nitromethane under mild conditions gives symmetrical 1,1 -binaphthyls in good yields. The method is particularly useful when applied to substrates with electron donating groups.