𝔖 Bobbio Scriptorium
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Selective Stimulation of Neurotransmitter Release from Chick Retina by Kainic and Glutamic Acids

✍ Scribed by Ricardo Tapia; Clorinda Arias


Book ID
111172139
Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
805 KB
Volume
39
Category
Article
ISSN
0022-3042

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In order to contribute evidence leading to establishing the excitatory pathways in the vertebrate retina, we selectively lesioned chick retinas by intraocular injection of 6, 60, 120, and 200 nmol of kainate, which selectively damages OFF-bipolars, amacrines, horizontals, and ON-bipolars, and measur

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Effects of glutamic, aspartic, and cysteic acid, and of kainic acid and N-methyl aspartate on the release of labeled GABA, glycine, and taurine were examined in isolated, perfused chick retina. Glutamic acid (0.5-2 mM), increased the release of 3H-GABA by more than four times and that of 14C-glycine