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Selective separation, detection of zotepine and mass spectral characterization of degradants by LC–MS/MS/QTOF

✍ Scribed by Talluri, M.V.N. Kumar; Kandimalla, Naveen Reddy; Bandu, Raju; Chundi, Divya; Marupaka, Ramesh; Srinivas, Ragampeta

Book ID
120433353
Publisher
Elsevier
Year
2014
Tongue
English
Weight
764 KB
Volume
4
Category
Article
ISSN
2095-1779

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## Abstract The metabolic profile of BAL4815, an antifungal azole drug, was determined using __in vitro__ rat hepatocyte incubations and subsequent analysis by capillary LC‐qTof‐MS and MS/MS including accurate mass determination. For the detection of the metabolites, a mixture of the drug and its d