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Selective removal of copper bound to metallothionein in the liver of LEC rats by tetrathiomolybdate

โœ Scribed by Kazuo T. Suzuki; Kyoko Yamamoto; Sanae Kanno; Yasunobu Aoki; Noritoshi Takeichi


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
571 KB
Volume
83
Category
Article
ISSN
0300-483X

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Dietary copper (Cu)- and age-dependent c
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To understand the unique pathophysiological process of LEC rats (Long-Evans rats with a cinnamon-like coat color), which develop hereditary and spontaneous hepatic injury โˆผ4 months after birth, the levels of four biometals, such as Cu, Fe, Zn, and Mn together with metallothionein (MT) and nitric oxi