Selective Reinforcement Learning Deficits in Schizophrenia Support Predictions from Computational Models of Striatal-Cortical Dysfunction

Single dose of a dopamine agonist impair

Single dose of a dopamine agonist impairs reinforcement learning in humans: Evidence from event-related potentials and computational modeling of striatal-cortical function

✍ Diane L. Santesso; A. Eden Evins; Michael J. Frank; Erika C. Schetter; Ryan Bogd 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 403 KB

## Abstract Animal findings have highlighted the modulatory role of phasic dopamine (DA) signaling in incentive learning, particularly in the acquisition of reward‐related behavior. In humans, these processes remain largely unknown. In a recent study, we demonstrated that a single low dose of a D2/