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Selective regulation of autoreactive B cells by FcγRIIB

✍ Scribed by Jeganathan Venkatesh; Daisuke Kawabata; Sunjung Kim; Xiaonan Xu; Prameladevi Chinnasamy; Elahna Paul; Betty Diamond; Christine M. Grimaldi

Book ID
116614203
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
379 KB
Volume
32
Category
Article
ISSN
0896-8411

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The fact that B cells undergo feedback suppression, or negative signaling, through the interaction of secreted antibody with specific antigen has been extensively documented but the mechanisms involved in the process have been elusive. Experiments over the past year using B cell deletion mutants and