Selective reduction of 3-keto group in steroidal ketoaldehydes
β Scribed by M.Paglialunga Paradisi; G.Pagani Zecchini
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 189 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4020
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WE have described in preceding publications 192 the preparation of 4-hydroxy-3-ketod4-steroids from the corresponding 3-keto-4,5-epoxides. In this paper we report a new method for the synthesis of this class of compounds, consisting in the oxidation of 3-keto-$-steroids in alkaline solution in the p
THE ground state oouformations of the steroid ring systems are in general securely looked in potential wells, can vary but little, and are for the most part well understood. In a 4,4-dimethyl-3-keto-5gC-steroid (I) however, there is reason to question whether or not ring A will be in the standard ch