Selective reduction in trabecular volumetric bone mineral density during treatment for childhood acute lymphoblastic leukemia
β Scribed by J.A. Kohler; R.J. Moon; R. Sands; L.J. Doherty; P.A. Taylor; C. Cooper; E.M. Dennison; J.H. Davies
- Book ID
- 119204175
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 194 KB
- Volume
- 51
- Category
- Article
- ISSN
- 8756-3282
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Children with acute lymphoblastic leukemia (ALL) often develop bone pain, abnormal gait, and unusual fractures while in remission and receiving continuing chemotherapy. A prospective longitudinal cohort study was undertaken of bone mass and biochemical mineral status in 40 consecutive children (27 m
## Abstract During recent decades, the survival rate after childhood acute lymphoblastic leukemia (ALL) has improved substantially; consequently, the longβterm side effects of ALL and its treatment have gained attention, of which osteoporosis is one of the most important. The purpose of the present