✦ LIBER ✦

Selective pressures and ras activation in carcinogenesis

✍ Scribed by Brandt L. Schneider; G. Tim Bowden

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 509 KB
Volume: 6
Category: Article
ISSN: 0899-1987
DOI: 10.1002/mc.2940060102

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The molecular progression of plutonium-2

The molecular progression of plutonium-239–induced rat lung carcinogenesis: Ki-ras expression and activation

✍ Bryan L. Stegelmeier; Nancy A. Gillett; Alan H. Rebar; Gregory Kelly 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 874 KB

Specific, transforming point mutations of ras and alterations in ras expression have been associated with many neoplastic processes, and their presence may be pivotal in neoplastic transformation. Our objective were to evaluate the molecular and genetic alterations of Ki-ras in preneoplastic foci an

Telomerase activation in colorectal carc

Telomerase activation in colorectal carcinogenesis

✍ Yan, Pu; Saraga, Emilia P.; Bouzourene, Hanifa; Bosman, Fred T.; Benhattar, Jean 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB 👁 2 views

Telomerase activity has been detected in germ cells as well as in the developing embryo. Activity is no longer detectable in most somatic cells of the neonate, although low levels of activity persist in regenerative tissues. Telomerase has been found to be reactivated or up-regulated in the majority

Distinct functions of H-Ras and K-Ras in

Distinct functions of H-Ras and K-Ras in proliferation and survival of primary hepatocytes due to selective activation of ERK and PI3K

✍ Carola M. Rosseland; Lene Wierød; Liv I. Flinder; Morten P. Oksvold; Ellen Skarp 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 400 KB

## Abstract Ras proteins mediate signals both via extracellular signal‐regulated kinase 1 and 2 (ERK), and phosphoinositide 3‐kinase (PI3K). These signals are key events in cell protection and compensatory cell growth after exposure to cell damaging and pro‐apoptotic stimuli, thus maintaining homeo

K-ras activation and ras p21 expression

K-ras activation and ras p21 expression in latent prostatic carcinoma in Japanese men

✍ Noboru Konishi; Takayuki Enomoto; Gregory Buzard; Masato Ohshima; Jerrold M. War 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 761 KB

Oncogenic K-ras promotes early carcinoge

Oncogenic K-ras promotes early carcinogenesis in the mouse proximal colon

✍ Shelly R. Calcagno; Shuhua Li; Migdalisel Colon; Pamela A. Kreinest; E. Aubrey T 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 981 KB

## Abstract Oncogenic __K‐ras__ mutations are frequently observed in colon cancers and contribute to transformed growth. Oncogenic __K‐ras__ is detected in aberrant crypt foci (ACF), precancerous colonic lesions, demonstrating that acquisition of a __K‐ras__ mutation is an early event in colon carc

Selective pressures and dental evolution

Selective pressures and dental evolution in hominids

✍ Patricia Smith 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 470 KB 👁 2 views

## Abstract Inter‐group differences in tooth size and attrition scores in fossil hominids from the late Riss, Würm I–II and Würm III–IV were compared to determine: (1) the extent and timing of reduction in tooth size; (2) the relation of such reduction to decreased functional demands made on the de