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Selective noradrenergic vulnerability in alpha-synuclein transgenic mice

โœ Scribed by Evangelos Sotiriou; Demetrios K. Vassilatis; Miquel Vila; Leonidas Stefanis

Book ID
116781445
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
948 KB
Volume
31
Category
Article
ISSN
0197-4580

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(Oligodendro)glial cytoplasmic inclusions composed of the protein alpha-synuclein (alphaSYN) are the neuropathological hallmark lesions of multiple system atrophy (MSA). The recent generation of transgenic mouse models of oligodendroglial alpha-synucleinopathy has enabled studies to investigate how