Selective mono O-alkylation of γ-resorcylic esters
✍ Scribed by R.J. Bass; B.J. Banks; M. Snarey
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- French
- Weight
- 89 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
The O-silylated dienolates of unsaturated ketones and esters can be alkylated using zinc bromide catalysis to give predominantly the y-alkylated carbonyl compounds. The substitution pattern of the substrate (11, favours, in certain cases, very high or complete y-selectivity.
O-Alkylation of cyclic thiohydroxamic acids 1 and 3-5 has large countercations, such as M = NBu 4 , are treated with hard alkylating reagents in polar aprotic media. (iv) As been studied with a view to developing an efficient method for the synthesis of N-(alkoxy)pyridine-2(1H)-thiones and N-tetrabu